Scientific Researcher / Senior Scientific Researcher - Small Molecule Process Chemistry
Genentech
 South San Francisco, CA

Genentech, a leader in bio-pharmaceutical sciences, is seeking a highly motivated and talented researcher with a proven track record of laboratory achievements to join our growing Department of Small Molecule Process Chemistry. Responsibilities of the position include:

  • Discover, develop and demonstrate process chemistry at the laboratory and kilo lab scale for timely delivery of early and mid-phase small molecule development candidates in accordance with cGMP, ICH and FDA/EMA regulations
  • Control the bulk quality attributes of the API conducive to successful development and formulation requirements
  • Interact with cross functional team members and CMO partners
  • Interpret and document results via batch records and milestone development reports
  • Keep current with developments in the field through peer-reviewed journals and other media, and maintain a scientific profile both internally and externally

The ideal candidate will meet the following requirements. The level of the position will depend on the qualifications of the selected candidate:

  • BS with 3+ years of relevant experience or MS in chemistry. Candidate with MS in organic chemistry is highly preferred.
  • Must have record of innovation and success in multiple projects over the course of their industrial career to be considered for the more senior level
  • A publication record is desirable, but candidates without peer-reviewed publications will also be considered for the Scientific Researcher level. Candidates with a proven record of scientific publication may be considered for the Sr. Scientific Researcher level.
  • Strong working knowledge of the latest developments in contemporary process chemistry including chemo- and/or bio-catalysis/asymmetric transformations, organometallic chemistry as well as experience in heterocyclic chemistry.
  • Demonstrated experience at the kilogram delivery scale and route optimization is strongly preferred, but candidates of exceptional promise without this experience will also be considered.
  • The ability to take initiative, solve problems independently, work in teams and communicate clearly, both orally and written, are essential skills for this position.

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