Candidate will be hired at level commensurate with experience
A key scientific staff member of the
Cancer Immunology and Immune Modulation (CI&IM) Research Group at
Boehringer Ingelheim’s US research facility in Ridgefield, CT, the successful
candidate will lead research efforts focusing on novel animal models for cancer
immunotherapy drug discovery and in vivo mechanism of action (MOA) studies to
support target validation, candidate selection and biomarker discovery of novel
immune-based concepts for cancer and inflammation therapy at BI.
As an employee of Boehringer
Ingelheim, you will actively contribute to the discovery, development and
delivery of our products to our patients and customers. Our global presence
provides opportunity for all employees to collaborate internationally, offering
visibility and opportunity to directly contribute to the companies' success. We
realize that our strength and competitive advantage lie with our people. We
support our employees in a number of ways to foster a healthy working
environment, meaningful work, diversity and inclusion, mobility, networking and
work-life balance. Our competitive compensation and benefit programs reflect
Boehringer Ingelheim's high regard for our employees.
Duties & Responsibilities:
- Develop, establish and coordinate innovative in vivomodel development to evaluate the stromal and immune modulatory effects ofnew therapeutic concepts (NTCs), for anti-tumor efficacy demonstration andcandidate selection, as well as to explore MOA and biomarkers.
- Independently drive in vivo and ex vivo studies formultiple research programs across the different stages of preclinical drugdiscovery and advancement of BI’s oncology pipeline.
- Independently responsible for authoring animalprotocols and ensuring their authorization and compliance.
- Train and direct research scientists - may havesupervisory responsibilities as needed including recruiting, managing,mentoring and developing scientific staff.
- Collaborate extensively with other members of theCancer Immunology and Immune Modulation Group in Ridgefield and globallyfor protocol development and execution of studies, while synergizingeffectively with the in vivo pharmacology group in the Inflammation &Respiratory therapeutic area.
- Prepare and review clear and accurate technical andresearch reports for internal and external use. Prepare and deliver scientificpresentations for internal/external use. Act as an experienced resource inproject teams, and demonstrate clear and professional verbal and writtencommunication.
- Continue to develop scientific expertise, credentialsand drug development expertise by keeping abreast of relevant literature,by expanding scientific/technical knowledge and skill sets, and bypublishing in peer-reviewed journals and speaking atinternationally-recognized scientific conferences.
Senior Scientist Requirements:
- PhD from an accredited institution orequivalent experience in a related field.Post-doctoralfellowship work experience is highly desired.
Principal Scientist Requirements:
- PhD with a minimum of 5 years ofpost-doctorate training and/or industrial experience.
- Proven track record of supervisingscientists and students.
Requirements for both levels:
- Strong understanding of cancerimmunity, including myeloid and fibroblastic components of the tumormicroenvironment and stroma and their influence on T cell biology.
- Strong understanding of mouse immunologyand cancer immunology, with exceptional in vivo experimental skills. Priorhands-on experience with mouse models of immunotherapy (e.g. syngeneicmouse tumor models, genetically-engineered mouse tumor models) anddeveloping novel in vivo models to assess the effects of novel therapeuticconcepts are a must. Experience with efficacy andpharmacokinetic/pharmacodynamics (PK/PD) and biomarker studies is a plus.
- A demonstrated track record ofindependent research and peer-reviewed publications in areas of cancerimmunology research. Familiarity with assessing the anti-tumor activity ofcancer immunotherapeutics using humanized mouse models is a plus.
- Excellent oral and writtencommunication skills, with the ability to propose, articulate, evaluateand defend scientific ideas and data.
- The ability to mentor anddevelop scientific staff
- The ability and willingness towork effectively in a highly collaborative research environment - withcolleagues in Germany, Austria and the USA including occasional travel toglobal research sites.
- The ability to both conduct independentresearch and be a team player.
- The ability to prioritizeresponsibility and be comfortable with changing direction/priorities.
Must be legally
authorized to work in the United States without restriction.
Must be willing to
take a drug test and post-offer physical (if required)
Must be 18 years of
age or older
Who We Are:
At Boehringer Ingelheim we create value through innovation
with one clear goal: to improve the lives of patients. We develop breakthrough
therapies and innovative healthcare solutions in areas of unmet medical need
for both humans and animals. As a family owned company we focus on long term
performance. We are powered by 50.000 employees globally who nurture a
diverse, collaborative and inclusive culture. Learning and development for
all employees is key because your growth is our growth.
Want to learn more?
and join us in our effort to make more health.
Boehringer Ingelheim, including Boehringer Ingelheim
Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Animal
Health USA Inc., Boehringer Ingelheim Animal Health Puerto Rico LLC and
Boehringer Ingelheim Fremont, Inc. is an equal opportunity and affirmative
action employer committed to a culturally diverse workforce. All qualified
applicants will receive consideration for employment without regard to race;
color; creed; religion; national origin; age; ancestry; citizenship status,
marital, domestic partnership or civil union status; gender, gender identity or
expression; affectional or sexual orientation; pregnancy, childbirth or related
medical condition; physical or psychiatric disability; veteran or military
status; domestic violence victim status; genetic information (including the
refusal to submit to genetic testing) or any other characteristic protected by
applicable federal, state or local law.