Associate Scientist, Virus Production

WuXi AppTec Philadelphia, PA
Overview

Independent scientist who demonstrates innovative technical knowledge and significantly contributes to the overall operations of the Virus Production group. Demonstrates strong oral and written communication skills and actively contributes to training, report generation and documentation. Contributes to the achievement of the company and departmental goals and objectives. Supports management of laboratory schedule with operations team. Performs and directs assays according to and in compliance with Good Laboratory Practice (GLP), current Good Manufacturing Practice (cGMP), Code of Federal Regulations (CFR) and/or Points to Consider (PTC) guidelines and Standard Operating Procedures (SOPs). Acts as Study Director as required.

Responsibilities

* Proficient on GE AKTA Explorer 100, AVANT 25, and AVANT 150

* Purification of viruses using batch records and protocols

* Demonstrates innovative and independent scientific technical expertise and proficiency in scientific theory and rigorous practical application in the completion of laboratory procedures and development of new procedures

* Designs and independently conducts scientific development projects from inception to completion

* Effectively communicates and defends science through written and verbal communication

* Provides training on areas of technical expertise and compliance issues relevant to the lab setting

* Conducts and directs assays and lab procedures according to and in compliance with GLP, cGMP, CFR and/or PTC guidelines and SOPs

* Accurately completes batch records and other required documentation according to and in compliance with GLP, cGMP, CFR and/or PTC guidelines and SOPs

* Prepares protocols, final reports, investigations, and deviations as needed

* Conducts critical review of results and reports data appropriately

* As assigned by Management, acts as Study Director, and/or Principal Investigator for specific assays and assumes all associated responsibilities

* Maintains a laboratory notebook for Research & Development activities as required; reviews and signs laboratory notebooks

* Follows all general and laboratory SOP

* Communicates with supervisor and other colleagues re: daily lab activities

Position Specific Responsibilities:

* Purification of Viruses

* Technical review of documents

* Perform R&D experiments to optimize the current state of viruses

* Troubleshoot issues related to virus performance

Qualifications

* Possesses knowledge of protein purification process

* 3+ years experience designing/developing/experimenting with column chromatography.

* Experience with GE AKTA equipment or equivalent

* Experience with Unicorn Software or equivalent

* Knowledge of GLP and cGMP preferred

* Effective multi-tasking skills and time management required

* Ability to evaluate technical data and record data accurately and legibly

* Ability to accurately and reproducibly perform complex mathematical and statistical calculations

* Ability to use judgment as dictated by complexity of situations

* Ability to understand and follow verbal and demonstrated instructions

* Ability to clearly express and exchange ideas by means of verbal and written communication

* Ability to work effectively as part of a team and exhibit effective interpersonal skills

* Ability to work under limited supervision and to handle problems of a difficult nature

* Ability to perform light physical work, lifting up to 20 pounds as needed, and performing activities such as repetitive motions

* Clarity of vision at all ranges, depth perception, and ability to identify and distinguish colors

* Bachelor's degree with major in Biological Sciences or other science-related major and 4 + years' experience OR Master's degree with major in Biological Sciences or other science-related major and 2+ years' experience

Equal Opportunity Employer Minorities/Women/Veterans/Disabled