Postdoctoral positions are available immediately to join Volsky Laboratory in Medicine/Infectious Diseases, at Icahn School of Medicine at Mount Sinai, New York. The fellows will be involved in the design, implementation, and analysis of in vitro and in vivo experiments to study the virological and neuropathological mechanisms of HIV induced cognitive disease in mice using virological, molecular-biological, neurobiological, and animal-behavioral techniques. Studies in mice will employ chimeric, mouse-tropic HIV-1 and will include construction and evaluation (in vitro and in vivo) of new chimeric viruses, analysis of mouse cells and tissues, confocal microscopy, and culture and evaluation of primary lymphoid and brain-derived cells. Participation in ongoing studies on HIV-1 replication in mice, latent HIV reservoirs in vivo, nano-medicine based antiviral therapy, and preclinical testing of interventions for cognitive impairment will be encouraged. It is anticipated that the fellows will contribute both intellectually and technically to these research efforts and will be expected to communicate his/her research effectively to colleagues and peers.