Associate Director, Genome Sequencing Shared Resource Core (Durham, NC, US, 27710)

Duke University
 Durham, NC

School of Medicine:

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Associate Director, Genome Sequencing Shared Resource


The successful candidate for this position will become the Associate Director of the Genome Sequencing Shared Resource within Duke’s Center for Genomic and Computational Biology. The candidate will manage and direct the daily activities of the Shared Resource. The candidate will work closely with the Director for resolving workload and technical issues as well as discussing strategic planning. The incumbent’s regular responsibilities will include:

  • Screening and assigning workload, tasks, and projects
  • Testing and launching new sequencing services
  • Delivering sequencing services according to provided timelines and quality goals
  • Overseeing data delivery, quality control, archiving, and analysis
  • Assisting with development and maintenance of data analysis pipelines
  • Contributing to the improvement of laboratory and data science efficiency
  • Working with the Director to identify and educate potential new clients for the Shared Resource

The candidate will consult and collaborate with interdisciplinary teams of researchers and scientists throughout Duke’s campus on projects utilizing high-throughput next-generation sequencing. Due to the need to engage in multiple collaborations simultaneously, it is critical that this person has excellent organizational skills, and the ability to manage and prioritize commitments to projects effectively. In conjunction with the Director, this person will oversee the recruitment, selection, and performance of the Shared Resource staff. This position reports to the Director.

The above statements describe the general nature and level of work being performed by individuals assigned to this classification. This is not intended to be an exhaustive list of all responsibilities and duties required of personnel so classified.


Required knowledge, skills and abilities

  • Extensive knowledge and hands-on experience of genomics techniques, particularly next-generation sequencing (including sample preparation and library construction).
  • Strong knowledge and experience with programing (Python, R, and shell preferred), public databases, bioinformatics tools (particularly for Next-Generation sequencing analysis; machine learning methods a plus), and familiarity with Unix environment and file management.
  • Supervision or mentoring experience.
  • Consulting experience and proposal preparation experience is a plus.
  • Good written and oral communication skills. Publication track record in genetics, genomics, or Next-Generation sequencing strongly preferred. Publication of new bioinformatics tools is a plus.
  • Teaching experience (lectures, workshops).
  • Ability to perform and prioritize multiple tasks, projects and demands.
  • Ability to establish and maintain working relationships with administration, client, and the shared resource staff.

Minimum required education and experience

  • Ph.D or equivalent doctorate (e.g. Sc.D., M.D., D.V.M).
  • Other Credential / Experiential Requirements: 5+ years of postdoctoral experience conducting scientific research. Multiple publications and notable significant contributions to scientific research.

Preferred Qualifications

  • PhD degree in genetics, genomics, bioinformatics, or computational biology.
  • Experience in RNA and DNA sequencing and significant knowledge and experience with next-generation technologies are strongly preferred.
  • Experience with Illumina technologies is preferred. Familiarity with other technologies is a plus.

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Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.