Research Associate, Immunology
Repertoire Immune Medicines
 Cambridge, MA

We are Repertoire Immune Medicines working to unleash the remarkable power of the human immune system. We seek to harness the intrinsic ability of T cells to prevent and cure disease. Our mission requires a complex and multi-dimensional approach that integrates cutting-edge biology and sophisticated, novel technologies. We stand ready to meet this challenge with our unique platforms, world-class team and unparalleled network of researchers, clinicians, academics and entrepreneurs.

We are looking for an outstanding Research Associate to work in the Antigen Processing and Presentation group. The Research Associate will assume a key role in developing novel immunological assays in support of Repertoire proprietary therapeutics. The ideal candidate will have a proven track-record of developing creative and novel immunology based assays for solving complex biological problems, as well as a broad understanding of therapeutic drug discovery and its applications, related to treatment of immunological based diseases. The Research Associate will have strong interpersonal skills, be driven by making great products, and enjoy working in a truly multi-disciplinary environment. This position will interact closely with colleagues in immunology, protein engineering, platform technology, and computational biology.

Key Responsibilities:

  • Culture of cell lines and primary human cells
  • Develop and validate immunological assays to measure modulation of immune cell functionality
  • Generate cell lines to support cell-based functional assays
  • Create and perform innovative assays to improve the phenotypic characterization of immune cells
  • Plan and execute systematic assay optimization
  • Interpret data, troubleshoot experiments and present results
  • Maintain and implement good laboratory practices, including accurate laboratory notebook systems, instrument and reagent validation, and personnel safety precautions

Minimum Qualifications:

  • BS or MS in immunology, molecular biology, biochemistry, or a similar field
  • > 3 years of pharmaceutical industry experience
  • Proven ability to develop and perform biochemical assays such as ELISA, immunoprecipitation, and Western blotting
  • Working knowledge of expressing target proteins from one or more expression systems (mammalian, bacterial, insect, etc.)
  • Working experience in flow cytometry is a plus
  • In depth experience in developing assays utilizing primary human cells/tissues
  • A strong desire to build game-changing technologies and impact the world of life science research
  • Strong organizational skills
  • Strong written and oral communication skills
  • Ability to work in a fast-paced and quickly changing environment
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