Director, Clinical Pharmacology

Celgene Corporation Cambridge, MA

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing we look for talented people to grow our business, advance our science and contribute to our unique culture.

Celgene seeks highly impactful new therapies for patients with poorly-treatable diseases – an endeavor posing formidable challenges. Despite impressive progress in reductionist science, yawning gaps remain in the understanding of integrated human biology. This results in failure of most drug candidates during clinical testing. Therapeutic advances thus demand synthesis of knowledge from the full spectrum of academic and industrial research to bridge those gaps. Quoting Louis Pasteur, "Fortune favors the prepared mind." The person filling this position will be part of Celgene's "prepared mind" – weaving curiosity, insight, and disciplined work into novel medicines.


* Plan and execute the following:

o clinical pharmacology studies for medicines development from first-in-human through post-marketing phases;

o innovative small studies in patients to support advancement of drug candidates to Phase 2;

o biomarker qualification studies.

* Work with statisticians, laboratory colleagues and project team-members to optimally interpret and report results of completed studies.

* Design early development plans for drug candidates.

* Contribute to regulatory filings, dossiers, and updates. Collaborate with counterparts in regulatory agencies.

* Work with external and internal scientists to identify and validate new drug targets and related biomarkers.

* Work on cross-disciplinary teams to evaluate outside opportunities for licensing or acquisition.

* Engage in continuous learning around basic and clinical science.

* Facilitate ongoing improvement of research approaches in translational and clinical pharmacology.

* Represent Clinical Pharmacology on project teams and in governance proceedings.

* Mentor and direct others as needed.

* Travel as needed to other Celgene sites, academic and biotech collaborating sites, regulatory meetings, and professional/scientific meetings. (5%-10%)

* LI-JW1



* MD

* PhD, or equivalent research training and background

* Residency training

* 3+ years of demonstrable and relevant clinical and/or bench research experience

* Conversational familiarity with science outside of research specialty

* Strong verbal and written communication skills

* Demonstrated ability to collaborate in multidisciplinary efforts

* Ability to live in the Boston area

* Working familiarity with inflammation, immunity, or ageing-related biology

* Clinical subspecialty training

* Pharmaceutical / biotech industry experience

* Experience in human pharmacology or translational science

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

Req ID: 16000409

Primary Location: United States--CAMBRIDGE2

Job: Research and Early Development

Organization: Celgene Corporation

Schedule: Regular

Shift: Standard

Employee Status: Director

Job Type: Full-time

Job Level: Day Job

Travel: Yes, 10 % of the Time

Job Posting: 2016-03-09 00:00:00.0

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